Resveratrol's bibliometric and visual analysis from 2014 to 2023.

Area of Science:

• Biomedical Science
• Pharmacology
• Natural Products Research

Background:

• Resveratrol (RSV) is a natural polyphenol with extensive biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties.
• Its potential for treating diverse diseases makes it a promising therapeutic agent.
• RSV's broad spectrum of activities necessitates a comprehensive overview of its research landscape.

Purpose of the Study:

• To quantitatively and qualitatively analyze the global research output on resveratrol from 2014-2023.
• To identify key trends, influential countries, institutions, authors, and publications in RSV research.
• To highlight emerging research areas and future directions for resveratrol studies.

Main Methods:

• Bibliometric analysis of 16,934 resveratrol-related papers.
• Utilized Web of Science Core Collection (WoSCC) database.
• Employed CiteSpace and VOSviewer for data visualization and analysis.

Main Results:

• Annual publication output shows a consistent upward trend, averaging 1693.4 papers per year.
• China leads in publications, with China Medical University being a highly productive institution.
• Key research themes include oxidative stress, apoptosis, and the effects of dietary polyphenols, with emerging focus on nanoparticle integration.

Conclusions:

• Resveratrol research is a dynamic and growing field with significant global contributions.
• Nanoparticle-based delivery systems and the development of novel RSV derivatives are key future research avenues.
• RSV demonstrates potential in various medical applications, including gut health, bone formation, and neuroprotection, warranting further investigation into enhanced bioavailability and therapeutic strategies.