Disparity in trends and characteristics of early onset colorectal cancer: analysis from the National Inpatient Sample, 2016 to 2021
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View abstract on PubMed
Summary
This summary is machine-generated.Early onset colon cancer disproportionately affects minority groups and those with obesity or tobacco use. Further research is crucial to address this growing public health concern.
Area Of Science
- Oncology
- Public Health
- Epidemiology
Background
- Colon cancer is a leading cause of cancer death in the U.S.
- Increasing incidence of early-onset colon cancer presents a significant public health challenge.
- Limited recent data exists on early-onset colon cancer hospitalizations.
Purpose Of The Study
- To analyze trends and characteristics of colon cancer hospitalizations from 2016-2021.
- To compare early-onset (≤50 years) and normal-age colon cancer patients.
- To identify factors associated with inpatient mortality in colon cancer patients.
Main Methods
- Utilized the National Inpatient Sample (2016-2021).
- Categorized nonelective colon cancer hospitalizations into early-onset and normal-age groups (cut-off: 50 years).
- Analyzed demographic factors, comorbidities, and mortality risks.
Main Results
- Early-onset nonelective colon cancer accounted for 11.91% of total hospitalizations (26,903 cases).
- No significant temporal trends were observed between 2016 and 2021.
- Early-onset patients showed disproportionate representation of Black, Hispanic, and Asian American individuals, along with higher rates of obesity and tobacco use compared to the normal-age group.
Conclusions
- Demographic factors and comorbidities significantly impact early-onset colon cancer patients differently than older patients.
- Further research is essential to understand and combat the rising incidence of early-onset colon cancer.
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