Related Experiment Video
Updated: Jun 9, 2025

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Mid-jejunal diverticulitis with closed-loop bowel obstruction, strangulation, and contained perforation.
Tzu Han Huang1, Madeline Marker1, Torben Urdahl1
1University of Minnesota Medical School Minneapolis Minnesota USA.
Acute on chronic jejunal diverticulitis can cause rare complications like closed-loop bowel obstruction and contained perforation, presenting as acute abdomen. The potential link between polymyalgia rheumatica and diverticular disease warrants clinical consideration for patient management.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Rheumatology
Background:
- Jejunal diverticulosis, characterized by sac-like outpouchings, can lead to serious complications including diverticulitis, obstruction, abscess, perforation, and fistula formation.
- Complicated jejunal diverticulosis often presents with non-specific symptoms of acute abdomen, potentially leading to misdiagnosis and delayed treatment.
- The association between polymyalgia rheumatica (PMR) and diverticular disease is an area requiring further research, with potential implications for treatment strategies.
Purpose of the Study:
- To highlight the rare presentation of acute on chronic jejunal diverticulitis with closed-loop bowel obstruction and contained perforation as a critical differential diagnosis for acute abdomen.
- To discuss the potential association between polymyalgia rheumatica and diverticular disease and its clinical implications, particularly regarding steroid therapy.
Main Methods:
- Case report of a 76-year-old male with a history of PMR presenting with acute abdominal symptoms.
- Diagnostic workup included physical examination, laboratory tests (leukocytosis, elevated inflammatory markers), and CT scan with IV contrast.
- Surgical intervention involved exploratory laparotomy and resection of the affected jejunal segment.
Main Results:
- CT scan revealed a contained perforation and closed-loop small bowel obstruction in the mid-abdomen.
- Pathology confirmed acute on chronic jejunal diverticulitis with numerous diverticula contributing to the obstruction and perforation.
- The patient's presentation underscores the importance of considering rare pathologies in acute abdomen cases.
Conclusions:
- Closed-loop bowel obstruction and contained perforation secondary to acute on chronic jejunal diverticulitis are rare but crucial considerations in the differential diagnosis of acute abdomen.
- The potential association between diverticular disease and PMR necessitates careful management, especially concerning the risk of diverticular perforation with glucocorticoid therapy for PMR.
Related Concept Videos
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...

