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Published on: April 28, 2015
Progress on Carbon Dots with Intrinsic Bioactivities for Multimodal Theranostics
Hao Zhang1, Hao Liu1, Xiaohui Liu1
1State Key Laboratory of Digital Medical Engineering, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China.
Carbon dots (CDs) with inherent biological activity show promise for bioimaging and disease treatment. This review explores their synthesis, properties, and diverse applications in multimodal theranostics.
Area of Science:
- Multidisciplinary research integrating biology, physics, materials science, and chemistry.
- Focus on carbon dots (CDs) with intrinsic bioactivities.
Background:
- Carbon dots (CDs) are emerging nanomaterials with potential in biomedicine.
- Their intrinsic bioactivities, biocompatibility, and functionalities are key for theranostics.
Purpose of the Study:
- To review carbon dots (CDs) with intrinsic bioactivities and their applications in multimodal theranostics.
- To provide a comprehensive understanding by integrating multiple scientific disciplines.
Main Methods:
- Analysis of the relationship between synthesis, structure, and properties of CDs.
- Review of biological activities (anti-tumor, antibacterial, anti-inflammatory) of CDs.
- Summary of optical and electronic properties for biomedical applications.
Main Results:
- CDs exhibit diverse bioactivities and tunable physicochemical properties.
- Applications span bioimaging, optical diagnosis, and therapeutic interventions.
- Multimodal theranostic capabilities are highlighted.
Conclusions:
- Carbon dots with intrinsic bioactivities offer significant potential for advanced biomedical applications.
- An interdisciplinary approach is crucial for harnessing their full therapeutic and diagnostic capabilities.
- Further research into CDs promises breakthroughs in multimodal theranostics.
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