Evaluation of moderate periorbital cellulitis and home-based therapy in children (EPOCH study, Part 2): A prospective

Zachary McPherson1,2, Deepali Thosar1, Amie Donnelly3

  • 1Emergency Department, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.

Insights

Ambulatory care is a safe and effective strategy for moderate paediatric periorbital cellulitis, reducing hospital admissions. This approach allows children to receive intravenous antibiotics at home, improving community-based care.

Area of Science:

  • Ophthalmology
  • Pediatric Emergency Medicine
  • Infectious Diseases

Background:

  • Paediatric periorbital cellulitis often necessitates inpatient care for intravenous antibiotics due to concerns of orbital spread.
  • Current management strategies for moderate periorbital cellulitis typically involve hospital admission.

Purpose of the Study:

  • To evaluate the safety and efficacy of an ambulatory care model for managing children with moderate periorbital cellulitis.
  • To assess the feasibility of outpatient management for this condition.

Main Methods:

  • A prospective study enrolled 84 children (aged 1-16 years) with moderate periorbital cellulitis.
  • Eligible children received intravenous antibiotics and were discharged with a peripheral cannula for ambulatory care follow-up.
  • Descriptive statistics were used to analyze demographic and clinical data.

Main Results:

  • 62 out of 84 children (73.8%) were successfully managed via the ambulatory care pathway.
  • Children managed as inpatients did not show higher CRP or White Cell counts compared to those managed in ambulatory care.
  • Two children required inpatient admission due to deterioration; one needed ophthalmic surgery. No mortality or sight-threatening complications occurred.

Conclusions:

  • A dedicated ambulatory care pathway is a safe and effective strategy for moderate paediatric periorbital cellulitis.
  • This approach reduces hospital bed occupancy and facilitates community-based patient management.
  • Ambulatory care can be a viable alternative to inpatient admission for selected pediatric patients.
Abstract