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Updated: Apr 26, 2026
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Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline
Published on: January 5, 2017
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ECBD: European chemical biology database
Ctibor Škuta1, Tomáš Müller1, Milan Voršilák1
1CZ-OPENSCREEN: National Infrastructure for Chemical Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, Prague 14220, Czech Republic.
Nucleic Acids Research
|October 23, 2024
Summary
The European Chemical Biology Database (ECBD) provides open access to over 4.3 million chemical biology screening data points. This FAIR data repository supports scientific discovery by making diverse compound screening results findable and reusable.
Area of Science:
- Chemical Biology
- Bioinformatics
- Drug Discovery
Background:
- The European Chemical Biology Database (ECBD) is a central repository for EU-OPENSCREEN.
- It adheres to FAIR principles (Findability, Accessibility, Interoperability, Reusability).
- Data is made available under open access principles.
Purpose of the Study:
- To describe the ECBD as a comprehensive resource for chemical biology data.
- To highlight the data types and accessibility of the ECBD.
- To promote the use of ECBD data in scientific research.
Main Methods:
- The ECBD stores both positive and negative results from primary and counter-screening assays.
- Data is generated using a library of over 107,000 diverse compounds.
- Assay annotations are continuously enriched by user-supported projects and internal efforts.
Main Results:
- The database contains 89 deposited datasets (assays), with 48 publicly accessible.
- These datasets encompass approximately 4.3 million experimental data points.
- Remaining data will be published after a publication embargo period of up to 3 years.
Conclusions:
- The ECBD offers a valuable, FAIR-compliant resource for the chemical biology community.
- Publicly accessible data can be retrieved via UI, API, or database dump under CC-BY 4.0 license.
- The ECBD facilitates data sharing and accelerates research in chemical biology.
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