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Primary Immunodeficiency in the ICU: A Retrospective Multicentric Study

Lucile Duvaltier1, Nizar Joher1, Laurent Argaud2

  • 1Department of Medical Intensive Care and.

American Journal of Respiratory and Critical Care Medicine
|October 23, 2024
PubMed
Summary

No abstract available in PubMed .

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Immunodeficiency Diseases01:25

Immunodeficiency Diseases

911
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
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Development of Immunocompetence01:22

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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