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Related Concept Videos

Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Updated: Jun 9, 2025

Thermal Ablation for the Treatment of Abdominal Tumors
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Tumor ablation in children.

Giulia Cassanelli1, Guglielmo Paolantonio2, George Koshy Parapatt2

  • 1Interventional Radiology Unit, Bambino Gesù Children's Hospital, IRCCS, Piazza S. Onofrio 4, 00165, Rome, Italy. giulia.cassanelli@opbg.net.

Pediatric Radiology
|October 23, 2024
PubMed
Summary

Pediatric interventional radiology is increasingly using image-guided tumor ablation for solid tumors. This technique offers curative, debulking, or palliative effects for various tumor types in children.

Keywords:
AblationInterventionalOncologyPediatricPercutaneousRadiologyTumor

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Area of Science:

  • Pediatric Interventional Radiology
  • Oncology
  • Medical Imaging

Background:

  • Tumor ablation techniques are established in adults and increasingly adopted for pediatric patients.
  • Image-guided tumor ablation is a versatile procedure in pediatric oncology.
  • It applies to both benign and malignant pediatric solid tumors.

Purpose of the Study:

  • To highlight the growing importance and application of image-guided tumor ablation in pediatric interventional radiology.
  • To discuss the role of tumor ablation as a standalone or combined therapy for pediatric solid tumors.

Main Methods:

  • Review of established and emerging image-guided tumor ablation techniques.
  • Application of these techniques in the pediatric population.
  • Integration with other locoregional therapies.

Main Results:

  • Tumor ablation demonstrates efficacy in treating a diverse range of pediatric solid tumors.
  • The procedures can achieve curative, debulking, or palliative outcomes.
  • Successful application across various histological tumor types.

Conclusions:

  • Image-guided tumor ablation is a valuable and expanding tool in pediatric interventional radiology.
  • It offers versatile therapeutic options for pediatric solid tumors, alone or combined with other treatments.
  • The technique provides significant benefits for managing pediatric malignancies and benign tumors.