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Foscarnet eyedrops for the treatment of refractory herpetic keratitis
Caroline C Awh1, Austen N Knapp1, Jeffrey M Goshe1
1Cole Eye Institute, Cleveland Clinic, i-32, 9500, Euclid Ave, Cleveland, OH, 44195, USA.
Purpose:
The purpose of this case series is to describe the clinical course of patients receiving foscarnet eyedrops for the treatment of refractory herpetic keratitis.
Observations:
Six patients diagnosed with herpetic keratitis were treated with foscarnet 24 mg/mL (2.4%) eyedrops with resulting improvement in keratitis.
Conclusion:
Topical foscarnet may be a safe and effective treatment for herpetic keratitis in conjunction with, or as an alternative to, conventional antiviral therapy. This is an off-label use of foscarnet.
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