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Iodine Excess Is Associated with Thyroid Dysfunction Among the Elderly.

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Summary
This summary is machine-generated.

High iodine levels in drinking water are linked to increased thyroid dysfunction in the elderly. This study found elevated water and urinary iodine concentrations in those with thyroid issues, highlighting a significant risk.

Keywords:
High water iodineIodineThe elderlyThyroid dysfunction

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Area of Science:

  • Endocrinology
  • Environmental Health
  • Geriatrics

Background:

  • The impact of high water iodine levels on thyroid function in the elderly is not well understood.
  • Iodine is essential for thyroid hormone synthesis, but excessive intake can disrupt thyroid health.

Purpose of the Study:

  • To investigate the association between excessive iodine in drinking water and thyroid dysfunction in the elderly population.
  • To assess iodine nutrition status and its relationship with thyroid function in elderly individuals residing in Yuncheng, Heze, Shandong.

Main Methods:

  • A cross-sectional study involving 385 elderly patients with thyroid dysfunction and 385 propensity score-matched euthyroid controls.
  • Analysis of iodine concentrations in water, urine (urinary iodine concentration - UIC, 24-h urinary iodine excretion - 24-h UIE), and thyroid hormones from collected samples.

Main Results:

  • Elderly individuals with thyroid dysfunction exhibited significantly higher iodine intake from water and elevated urinary iodine levels compared to controls.
  • Logistic regression revealed that higher concentrations of iodine in cooking water, drinking water, UIC, and 24-h UIE were associated with increased odds of thyroid dysfunction.

Conclusions:

  • Elevated iodine levels in drinking water are a significant risk factor for thyroid dysfunction among the elderly.
  • The findings underscore the importance of monitoring water iodine content to prevent thyroid disorders in aging populations.