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THE RELATIONSHIP BETWEEN SERUM INFLAMMATORY CYTOKINES AND HYPERLIPIDEMIC ACUTE PANCREATITIS
1Department of Hepatobiliary Surgery, Jiaozhou Central Hospital of Qingdao, Qingdao, 266300 Shandong, China.
Abstract:
The incidence of hyperlipidemic acute pancreatitis (HLAP) has been increasing annually. However, it is unclear whether there is a correlation between serum inflammatory factors and HLAP. This study aimed to explore the relationship between serum inflammatory factors and HLAP.
Methods:
In this study, sixty patients with hyperlipidemic severe acute pancreatitis were registered from January 2020 to December 2024 at our hospital. Sixty healthy volunteers who underwent physical examination at the hospital physical examination center during the same period were selected as controls. Th1/Th2 cells, high-sensitivity C-reactive protein (hs-CRP), interleukin-17 (IL-17), tumor necrosis factor-alpha (TNF-α) were compared between two groups.
Results:
The BMI level of the HLAP group was higher than that of the control group. The levels of hs-CRP, IL-17, and TNF-α in the HLAP group were higher than those in the control group.
Conclusion:
High BMI, hs-CRP, IL-17, and TNF-α levels may be risk factors for HLAP.
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