Biomacromolecules-based nanoparticle formulations for the treatment of osteoporosis: A bibliometric analysis

This bibliometric analysis examined biomacromolecule-based nanoparticle formulations, emphasizing polysaccharides, for osteoporosis treatments from 2009 to 2024. Using the Web of Science database, we tracked around 141 publications, of which 117 were original research articles. This shows an emerging trend in biomacromolecule-based nanoparticle formulations based on the total number of publications. On further analysis, we found 61 original articles that focused on polysaccharides-based nanoparticles for drug delivery. This study also identified 'pharmacology and pharmacy,' 'materials science, biomaterials, and 'nanoscience and nanotechnology' as the primary research areas, emphasizing the field's interdisciplinary nature. The 'Journal of Drug Delivery Science and Technology' emerged as a significant journal for this research theme. Notable contributions came from the Egyptian Knowledge Bank and funding organizations like the National Natural Science Foundation of China. China, India, and Egypt are the top three research-productive countries in this field. This novel study underscores a dynamic, globally collaborative effort to advance polysaccharide-based nanoparticle applications in osteoporosis treatment. Based on the current publications, it also highlights challenges and future perspectives in the field.