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Updated: Jun 9, 2025

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
Published on: April 7, 2021
Noninvasive Respiratory Support in Acute Respiratory Distress Syndrome
Sergio Lassola1, Marco Giani2, Giacomo Bellani3
1Department of Anesthesia and Intensive Care, Santa Chiara Hospital, Largo Medaglie d'Oro 9, Trento 38122, Italy.
Abstract:
Noninvasive respiratory supports have been successfully used as an alternative to endotracheal intubation especially in patients with a milder degree of hypoxemia. In patients with acute respiratory distress syndrome (ARDS), the main goals of noninvasive oxygenation strategies are to improve oxygenation, unload the respiratory muscles, and relieve dyspnea. On the other hand, recent studies have suggested that spontaneous breathing could represent an additional mechanism of lung injury, especially in the more severe forms. The aim of this review is to describe the role of different noninvasive respiratory supports in ARDS, to optimize its use in clinical practice.
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