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Updated: Jun 9, 2025

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
Published on: April 7, 2021
Extracorporeal Support for Acute Respiratory Distress Syndrome
Richard Greendyk1, Darryl Abrams1, Cara Agerstrand1
1Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physicians and Surgeons, 622 W168th Street, PH 8E, 101, New York, NY 10032, USA.
Abstract:
Extracorporeal life support (ECLS) has a long history in the management of the acute respiratory distress syndrome (ARDS). The objectives of this review are to summarize the rationale and evidence for ECLS in ARDS including its role in reducing ventilator-induced lung injury (VILI), suggest best practice management strategies during ECLS, and identify areas that require additional research to better inform patient care.
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