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Updated: Jun 9, 2025

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Perioperative Considerations for Patients on GLP1 Agonists
Beth A VanderWielen1, William Brian Beam1
1Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA.
Abstract:
GlP-1 receptor agonists are a class of medications that are becoming increasingly popular. Large trials have shown that their use provides reliable weight loss in obese patients and improved glycemic control in diabetic patients. Its use also has broader implications for overall metabolic health and has been shown to improve cardiovascular outcomes in high-risk populations. Glucagon-like peptide 1 receptors cause multiple effects in the body through stimulation of receptors expressed in a broad range of tissues including the pancreas, liver, gastrointestinal tract, kidneys, heart, endothelium, muscle, and brain. For the anesthesia professionals the effects of these medications on gastric emptying is important.
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