Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bacterial Phylum Firmicutes

Bacterial Phylum Firmicutes

Firmicutes is a diverse phylum of Gram-positive bacteria characterized by a low GC content in their genomes. This phylum includes organisms with monoderm or diderm cell envelopes, highlighting a complex evolutionary history. Firmicutes comprises several major orders, including Lactobacillales, Clostridiales, and Bacillales, which exhibit remarkable diversity in their morphology, metabolism, and ecological roles.The order Lactobacillales includes lactic acid bacteria, which are fermentative...

Bacterial Phylum Actinobacteria

Bacterial Phylum Actinobacteria

Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...

Applications of Molecular Taxonomy

Applications of Molecular Taxonomy

Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...

Bacterial Phylum Proteobacteria

Bacterial Phylum Proteobacteria

Proteobacteria, one of the largest and most diverse bacterial phyla, encompasses a wide range of Gram-negative bacteria distinguished by their outer membrane composed of lipopolysaccharides. These microorganisms exhibit various metabolic capabilities, including phototrophy, chemolithotrophy, and heterotrophy, and thrive in diverse environments from soil to aquatic systems and host-associated niches. The phylum is divided into six classes: Alphaproteobacteria, Betaproteobacteria,...

Bacterial Phylum Bacteroidota

Bacterial Phylum Bacteroidota

The phylum Bacteroidota includes over 700 species classified into four primary orders: Bacteroidales, Cytophagales, Flavobacteriales, and Sphingobacteriales. These gram-negative, non-sporulating rods exhibit saccharolytic capabilities and can be aerobic or fermentative, encompassing obligate aerobes, facultative aerobes, and obligate anaerobes. Many species display gliding motility, though some are nonmotile or use flagella. The genus Bacteroides is well-studied due to its significant role in...

Bacterial Phylum Verrucomicrobiota

Bacterial Phylum Verrucomicrobiota

The phylum Verrucomicrobiota comprises at least four characterized orders, with most species classified within the order Verrucomicrobiotales. Members of this phylum are either aerobic or facultatively aerobic, with the ability to ferment sugars. A notable exception is the genus Methylacidiphilum, which consists of aerobic methanotrophs. Additionally, some Verrucomicrobiota establish symbiotic relationships with protists. These bacteria are widely distributed across various environments,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Performability evaluation, validation and optimization for the steam generation system of a coal-fired thermal power plant.

MethodsX·2022

Same author

A Comparative Study of Blood Loss With and Without Infusion of Tranexamic Acid in Total Knee Replacement.

Cureus·2022

Same author

Reply to Oren et al., "New Phylum Names Harmonize Prokaryotic Nomenclature".

mBio·2022

Same author

Ecological variations in adult life table attributes of Aedes aegypti (L.) from the desert and coastal regions of India.

Medical and veterinary entomology·2022

Same author

Registration of polarimetric images for in vivo skin diagnostics.

Journal of biomedical optics·2022

Same author

High interfacial charge separation in visible-light active Z- scheme g-C<sub>3</sub>N<sub>4</sub>/MoS<sub>2</sub> heterojunction: Mechanism and degradation of sulfasalazine.

Chemosphere·2022

Search research articles

Related Experiment Video

Updated: Jun 9, 2025

Use of MALDI-TOF Mass Spectrometry and a Custom Database to Characterize Bacteria Indigenous to a Unique Cave Environment Kartchner Caverns, AZ, USA

Use of MALDI-TOF Mass Spectrometry and a Custom Database to Characterize Bacteria Indigenous to a Unique Cave Environment Kartchner Caverns, AZ, USA

Published on: January 2, 2015

A unique bacterial family strikes again!

Gyanesh Shukla¹, Gaurav Sharma¹

¹Department of Biotechnology, Indian Institute of Technology Hyderabad, Sangareddy, Telangana, India.

Trends in Microbiology

|October 23, 2024

Summary

Researchers discovered Pendulisporaceae, a new myxobacterial family, containing four strains with unique gene clusters. This finding highlights the potential of underrepresented microbes for novel natural product discovery, particularly for antimicrobial and therapeutic applications.

Keywords:

biosynthetic gene clusters culturable bacteria microbial taxonomy myxobacteria secondary metabolites

More Related Videos

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Published on: July 11, 2016

Establishing Stable Binary Cultures of Symbiotic Saccharibacteria from the Oral Cavity

Establishing Stable Binary Cultures of Symbiotic Saccharibacteria from the Oral Cavity

Published on: April 13, 2021

Related Experiment Videos

Last Updated: Jun 9, 2025

Use of MALDI-TOF Mass Spectrometry and a Custom Database to Characterize Bacteria Indigenous to a Unique Cave Environment Kartchner Caverns, AZ, USA

Use of MALDI-TOF Mass Spectrometry and a Custom Database to Characterize Bacteria Indigenous to a Unique Cave Environment Kartchner Caverns, AZ, USA

Published on: January 2, 2015

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Published on: July 11, 2016

Establishing Stable Binary Cultures of Symbiotic Saccharibacteria from the Oral Cavity

Establishing Stable Binary Cultures of Symbiotic Saccharibacteria from the Oral Cavity

Published on: April 13, 2021

Area of Science:

Microbiology
Natural Product Chemistry
Genomics

Background:

Myxobacteria are known for producing diverse bioactive secondary metabolites.
Exploring underrepresented microbial taxa is crucial for discovering novel natural products.
Previous research has not extensively characterized the Pendulisporaceae family.

Purpose of the Study:

To identify and characterize a novel myxobacterial family.
To investigate the biosynthetic gene clusters within the newly identified family.
To assess the potential of this family for natural product discovery.

Main Methods:

Phylogenetic analysis of 16S rRNA gene sequences.
Whole-genome sequencing of isolated strains.
Bioinformatic analysis of biosynthetic gene clusters.
Comparative genomics.

Main Results:

Identification and formal description of the Pendulisporaceae family, a novel myxobacterial taxon.
Characterization of four distinct strains belonging to this new family.
Discovery of numerous novel biosynthetic gene clusters within the Pendulisporaceae genomes.
These gene clusters suggest potential for producing unique secondary metabolites.

Conclusions:

Pendulisporaceae represents a significant addition to the known diversity of myxobacteria.
The family harbors a rich repertoire of biosynthetic gene clusters, indicating a high potential for novel natural product discovery.
Further investigation of Pendulisporaceae is warranted to isolate and characterize new antimicrobial and therapeutic agents.