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Mapping the sclerostin-LRP4 binding interface identifies critical interaction hotspots in loops 1 and 3 of sclerostin

Svetlana Katchkovsky1, Reut Meiri2, Shiran Lacham-Hartman3

  • 1Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

FEBS Letters
|October 23, 2024
PubMed

Keywords:
LRP4SclerostinWnt/β‐catenin pathwaydeep mutational scanningepitope mappingyeast surface display

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