Related Experiment Video

Updated: Jun 9, 2025

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
08:45

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors

Published on: July 17, 2020

6.2K

Erratum To: Structural basis for specific inhibition of the highly sensitive ShHTL7 receptor

Umar Shahul Hameed, Imran Haider, Muhammad Jamil

    EMBO Reports
    |October 24, 2024
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Co-immunoprecipitation Assay for Studying Functional Interactions Between Receptors and Enzymes
    09:40

    Co-immunoprecipitation Assay for Studying Functional Interactions Between Receptors and Enzymes

    Published on: September 28, 2018

    15.1K
    Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b
    10:20

    Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b

    Published on: November 11, 2016

    8.5K

    Related Experiment Videos

    Last Updated: Jun 9, 2025

    Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
    08:45

    Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors

    Published on: July 17, 2020

    6.2K
    Co-immunoprecipitation Assay for Studying Functional Interactions Between Receptors and Enzymes
    09:40

    Co-immunoprecipitation Assay for Studying Functional Interactions Between Receptors and Enzymes

    Published on: September 28, 2018

    15.1K
    Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b
    10:20

    Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b

    Published on: November 11, 2016

    8.5K

    Related Concept Videos

    Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

    Ligand-Gated Ion Channel Receptor: Gating Mechanism

    2.1K
    Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
    2.1K

    Articles linked to this work by shared authors, journal, and citation graph.

    Biallelic EZH1 Nonsense Novel Variant in Two Siblings with Neurodevelopmental Disorder and Central Precocious Puberty: A Case Report from a Consanguineous Saudi Family.

    International journal of molecular sciences·2026

    Disseminated intravascular coagulation in chimeric antigen receptor T-cell therapy: a 6-year nationwide analysis of clinical outcomes and health care resource utilization in patients with hematologic malignancies.

    Research and practice in thrombosis and haemostasis·2026

    A Novel SLC25A4 Variant Causing Mitochondrial Dysfunction, Myopathy and Cardiomyopathy: A Functional and Molecular Characterization.

    International journal of molecular sciences·2026

    A Confidence-Aware Hybrid Vision-Language Framework for Food Recognition and Nutritional Monitoring.

    Nutrients·2026

    Assessment of S-metolachlor-Induced Biochemical and Histopathological Alterations in Cardiomuscular Systems of Domestic Chicks (Gallus gallus domesticus): A Toxicological Perspective.

    Journal of applied toxicology : JAT·2026

    Wildfire-induced suppression of anthropogenic sulfate formation in downwind regions of Northeast Asia.

    Environmental pollution (Barking, Essex : 1987)·2026

    Sulf1 regulates inflammation via modulation of TGF-β dependent epicardial activation.

    EMBO reports·2026

    DNA end-resection is stimulated by an interaction between BRCA1 exon 11 and TOPBP1.

    EMBO reports·2026

    Maternal microbiome promotes offspring ovarian reserve via bile acid metabolism.

    EMBO reports·2026

    PIWI proximity proteome reveals Set1-mediated piRNA biogenesis for transposon silencing at telomeres.

    EMBO reports·2026

    MPK3-mediated phosphorylation inactivates MYB4 to promote FIT-dependent iron acquisition.

    EMBO reports·2026

    The ER-Golgi intermediate compartment: a central hub integrating membrane trafficking and stress responses.

    EMBO reports·2026

    Cell-specific cPGES control of glucocorticoid receptor function drives MASLD progression.

    Cell reports·2026

    1-Aminocyclopropane-1-Carboxylate and Its Chemoreceptor Drive Metabolic Reprogramming to Enhance Chemotactic Rhizocompetence in Pseudomonas sp. UW4.

    Microorganisms·2026

    From Solvent Design to Biological Response: Structure-Property Relationships of Edible Natural Deep Eutectic Solvents for the Extraction of Nigella sativa Bioactives.

    Molecules (Basel, Switzerland)·2026

    Molecular Characterization and RNAi-Based Functional Validation of Ache in the Neonicotinoid Stress Response of the Melon Fly, Zeugodacus cucurbitae.

    Insects·2026

    Enhancing materials discovery with valence-constrained design in generative modeling.

    Nature computational science·2026

    Autonomous bioisosteric replacement for multi-property optimization in drug design.

    Nature communications·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us