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Mandibular bone imaging assessment in thalassemia - a systematic review
Larissa Conrado da Silva1, Pedro Albuquerque Counago Marques1, Bruna Cristina Oliveira Dos Santos1
1Department of Pathology and Oral Diagnosis, School of Dentistry, Universidade Federal do Rio de Janeiro, Niterói, Rio de Janeiro, Brazil.
Summary
Individuals with thalassemia show altered bone patterns on panoramic radiographs, specifically reduced fractal dimension analysis (FDA) and mandibular cortical width (MCW). These changes may indicate reduced bone mineral density (BMD) but require further research due to low evidence certainty.
Area of Science:
- Oral Medicine
- Radiology
- Hematology
Background:
- Thalassemia is a genetic blood disorder affecting hemoglobin production.
- Bone alterations, including reduced bone mineral density (BMD), are common in thalassemia patients.
- Panoramic radiography offers a non-invasive method to assess bone quality.
Conclusions:
- Fractal dimension analysis (FDA) and mandibular cortical width (MCW) are frequently altered in thalassemia patients.
- These parameters may serve as screening tools for reduced bone mineral density (BMD).
- The certainty of evidence is very low due to methodological limitations, necessitating further high-quality research.
