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Exercise During Chemotherapy for Cancer: A Systematic Review.
R C Walker1,2, P Pezeshki1,3, S Barman1,4
1Guy's & St Thomas' Oesophago-gastric Centre, London, UK.
Journal of Surgical Oncology
|October 24, 2024
Summary
Exercise prehabilitation enhances chemotherapy tolerance and effectiveness. This intervention improves body composition, fitness, strength, and quality of life (QoL) in cancer patients, offering a safe and effective supportive care strategy.
Area of Science:
- Oncology
- Exercise Science
- Cancer Rehabilitation
Background:
- Anticancer treatments like chemotherapy can be challenging for patients.
- Exercise prehabilitation is proposed to mitigate treatment side effects and improve outcomes.
- Understanding the specific benefits of exercise during cancer therapy is crucial.
Purpose of the Study:
- To systematically review the impact of exercise on chemotherapy outcomes.
- To identify research gaps and priorities in exercise oncology.
Main Methods:
- A systematic review of 19 studies (1418 patients) was conducted.
- Included studies comprised 11 randomized controlled trials and 8 observational studies.
- Data on body composition, fitness, strength, and quality of life were analyzed.
Main Results:
- Exercise interventions demonstrated significant improvements in body composition, fitness, and strength.
- Quality of life (QoL) was positively affected by exercise during chemotherapy.
- Exercise was found to be a safe and effective supportive care strategy.
Conclusions:
- Exercise prehabilitation is a viable and beneficial intervention for patients undergoing chemotherapy.
- Further research with larger, well-designed studies is needed to optimize exercise protocols.
- Standardization of exercise interventions is recommended for future research.
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