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Related Experiment Video

Updated: Jun 9, 2025

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
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Associations Between Physical Activity Patterns and Cardiovascular Events and Risk Factors: Cross-Sectional and

Fabrizio Cominetti1, Julien Vaucher1,2, Pedro Marques-Vidal1

  • 1Internal Medicine Division, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

JACC. Advances
|October 24, 2024
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Summary
This summary is machine-generated.

Timing of physical activity (PA) matters for cardiovascular disease (CVD) risk. Exercising in the early morning or throughout the day may increase CVD event risk, while specific patterns did not consistently affect risk factors.

Keywords:
cardiovascularchronoactivitychronotypeepidemiologyphysical activity

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Area of Science:

  • Cardiology
  • Preventive Medicine
  • Exercise Physiology

Background:

  • Moderate-intensity physical activity (PA) is recommended for health benefits.
  • The optimal timing of PA for cardiovascular disease (CVD) prevention remains debated.

Purpose of the Study:

  • To assess the impact of different physical activity (PA) patterns on cardiovascular disease (CVD) risk factors and outcomes.
  • To investigate the relationship between PA timing and CVD risk in a population-based cohort.

Main Methods:

  • Utilized data from two surveys (S1 and S2) of the CoLaus-PsyCoLaus study.
  • Assessed PA using wrist-worn accelerometers and K-means clustering for pattern analysis.
  • Included 2,465 (S1) and 1,692 (S2) participants, with a mean age around 61-64 years.

Main Results:

  • Early morning PA (7 am-12 am) was associated with a higher risk of CVD events (HR: 3.33).
  • Evenly distributed daily PA was also linked to increased CVD event risk (HR: 3.16).
  • No consistent associations were found between PA patterns and hypertension, blood lipids, or diabetes markers.

Conclusions:

  • Physical activity predominantly in the early morning or evenly distributed throughout the day may be associated with a higher risk of cardiovascular events.
  • Specific PA timing patterns did not show consistent associations with key CVD risk factors like hypertension or blood lipids.