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Intracholecystic Papillary Neoplasm: A Rare Case Report
Shubham N Bargaje1, Harshal Ramteke1, Aishwarya K Tare1
1Surgery, N.K.P. Salve Institute of Medical Sciences and Research Center, Nagpur, IND.
Cureus
|October 24, 2024
Summary
Intracholecystic papillary neoplasm (ICPN) is a premalignant gallbladder lesion that can progress to cancer. Early detection and intervention of gallbladder polypoidal masses are crucial to prevent malignancy.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Intracholecystic papillary neoplasm (ICPN) is a rare, noninvasive, premalignant epithelial neoplasm of the gallbladder.
- It arises from the gallbladder mucosa, projects into the lumen, and has the potential to progress to invasive gallbladder carcinoma.
- ICPN is often incidentally discovered during imaging or postoperative histological examination, frequently missed preoperatively.
Observation:
- A rare case of ICPN was diagnosed postoperatively in a 70-year-old female presenting with right hypochondrium pain.
- The patient's symptoms were non-specific, highlighting the diagnostic challenges of ICPN.
- Histopathological examination confirmed the diagnosis of ICPN.
Findings:
- The study presents a rare case of intracholecystic papillary neoplasm (ICPN).
- The diagnosis was confirmed postoperatively via histopathological examination.
- The patient presented with abdominal pain, a common but non-specific symptom.
Implications:
- Early detection and intervention of gallbladder polypoidal masses are critical.
- Prompt management can prevent the progression of benign or preinvasive lesions to invasive gallbladder carcinoma.
- This case underscores the importance of thorough histopathological evaluation for gallbladder lesions.
