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Development and Assessment of a Multipurpose Herbal Cream With Moringa oleifera Lam
Mythili Suresh1, Sri Kessav Mukundan1, Sivaraman Rajasekar1
1Department of Pharmacognosy, SRM College of Pharmacy, SRM Institute of Science and Technology, Chennai, IND.
Background:
Moringa oleifera Lam. (Moringaceae) is an indigenous tree extensively used as a nutrient and an antioxidant. In addition to its medicinal attributes, it possesses a promising role in moisturizing and cleansing the skin.
Objectives:
Our study aims to formulate an herbal cream from Moringa oil and evaluate its antimicrobial and anti-inflammatory activity.
Materials And Methods:
In the present study, Moringa oil was extracted from the seed kernels and formulated into an herbal cream, and the antimicrobial and anti-inflammatory activity was evaluated. Among the three formulations M1, M2, and M3, the formulation M1 was homogenous, more stable, and non-greasy with constant pH. M1 was subjected to further antimicrobial studies and anti-inflammatory studies by the agar-well diffusion technique and albumin denaturation assays, respectively.
Results:
M. oleifera seed kernel oil cream exhibited the highest antibacterial effect against Staphylococcus aureus and Escherichia coli, and the results were compared to the standard gentamycin. Moreover, M1 showed remarkable anti-inflammatory activity with an IC50 value of 124.5 μg/mL.
Conclusion:
The results show that the formulated cream will be efficient in its multipurpose activity. The current study validates the antibacterial and anti-inflammatory potential of M. oleifera seed kernel oil cream.
