Distribution of blood monocytes between a marginating and a circulating pool

Studies on the blood volume of SPF Swiss mice in the steady state led to reevaluation of the distribution of monocytes in the blood compartment. It was concluded from the results of our calculations that monocytes entering the circulation are distributed over a circulating and a marginating pool. The circulating pool accounts for approximately 40%, and the marginating pool or approximately 60% of the population of peripheral blood monocytes.