Related Experiment Video
Updated: Aug 7, 2026

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
Published on: July 29, 2011
Efficacy of the peak frequency map for left atrial posterior wall isolation
Shintaro Yamagami1, Suguru Nishiuchi1, Tomohiro Sato1
1Department of Cardiology, Tenri Hospital, Tenri, Nara, Japan.
Introduction:
Complete isolation of the left atrial posterior wall (LAPW) is challenging owing to overlapping epicardial conduction. Peak frequency (PF) is a novel parameter that focuses on near- and far-field electrogram components. In this study, we aimed to determine whether transmural block completion is related to the ablation site PF.
Methods:
We analyzed 44 consecutive patients undergoing initial LAPW isolation (LAPWI) between June 2023 and February 2024. Pre-LAPWI and PF maps were obtained using an HD-Grid catheter. In 17 of the 44 patients (Group-1), LAPWI was performed conventionally. In the remaining 27 patients (Group-2), PF-guided LAPWI was applied based on Group-1 results.
Results:
In Group-1, the left atrial (LA) roof and floor line success rates were 58.8% and 76.5%, respectively. The average PF value in the roof lines of patients with a completed block line was significantly higher than that of the remaining patients (286.6 ± 29.3 Hz vs. 236.1 ± 40.9 Hz, p = .012), but the floor lines were similar. In Group-2, relatively high PF values were targeted to achieve complete block of the LA roof and floor lines, following the results obtained in Group-1. The LA roof line success rates (92.6% vs. 58.8%, p = .007), total number of radiofrequency (RF) applications (22.7 ± 5.6 vs. 27.6 ± 8.5, p = .03), and procedural time (32.6 ± 18.3 vs. 47.9 ± 25.6 min, p = .03) differed between Group-1 and Group-2.
Conclusion:
Using a PF map for determining the optimal ablation line for LAPWI by RF catheter ablation is feasible.
Related Concept Videos
Relative Frequency Histogram
Expected Frequencies in Goodness-of-Fit Tests
Double Resonance Techniques: Overview
Spin decoupling is usually achieved by...
Bode Plots Construction
Effective Value of a Periodic Waveform
The effective value of a periodic current represents the direct current (DC) that conveys the same average power to a resistor as the periodic current itself. This concept is crucial when assessing AC circuits. To determine the...
Frequency Response of a Circuit
The transfer function is pivotal in characterizing how these circuits react to various frequencies, facilitating a profound understanding of their behavior. An essential parameter is the time constant, signifying the...

