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Multicentric Retrospective Study on Safety and Efficacy of a Novel Injectable Poly-l-Lactic Acid for Buttocks
Paola Rosalba Russo1, Bruno Bovani2, Francesca De Angelis3
1Private Practitioner, Esteemed Aesthetic Clinic, Modena, Italy.
Journal of Cosmetic Dermatology
|October 24, 2024
Summary
This study shows that GANA X, a poly-l-lactic acid (PLLA) filler, is safe and effective for buttock augmentation. Patients experienced significant aesthetic improvements and enhanced quality of life with minimal side effects.
Area of Science:
- Aesthetic Medicine
- Dermatology
- Biomaterials
Background:
- Poly-l-lactic acid (PLLA) injectables are increasingly used in aesthetic medicine for their biocompatibility and lasting effects.
- While primarily for facial rejuvenation, PLLA fillers show promise for off-label body treatments, demonstrating good efficacy and safety.
Purpose of the Study:
- To evaluate the safety and efficacy of a new 630 mg PLLA-based filler, GANA X, for non-surgical buttock augmentation.
Main Methods:
- Six Italian physicians administered GANA X to 51 patients for buttock aesthetic enhancement.
- Physician and patient surveys assessed treatment safety, efficacy, and impact on quality of life.
Main Results:
- Adverse events were minor, mild, and self-resolved within days.
- Both physicians and patients reported moderate to significant aesthetic improvements lasting up to 24 months.
- Patients reported increased self-esteem and improved quality of life post-treatment.
Conclusions:
- GANA X demonstrates high efficacy and tolerability for buttock augmentation.
- Physician and patient satisfaction is high, supporting its use in off-label body areas.
- Further research into PLLA fillers for body contouring is warranted.
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