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Published on: February 4, 2018
Cardiac Manifestations of Lyme Disease
Maisha Maliha1, Nathaniel Abittan2, William H Frishman3
1From the Department of Medicine, Jacobi Medical Center and Albert Einstein College of Medicine, Bronx, NY.
Insights
Lyme disease (LD) can cause cardiac complications in adults, affecting the heart
Area of Science:
- Cardiology
- Infectious Diseases
- Epidemiology
Background:
- Lyme disease (LD) is a common tick-borne illness in the US and Europe.
- Cardiac complications, known as Lyme carditis (LC), affect 1.5-10% of infected adults.
Purpose of the Study:
- To review current knowledge on Lyme carditis (LC).
- To highlight the effects of LD on the cardiac conduction system, myocardium, pericardium, valves, and coronary arteries.
- To discuss the diagnosis, management, and prognosis of LC.
Main Methods:
- Comprehensive literature review of Lyme carditis (LC).
Main Results:
- LD can manifest in various cardiovascular components.
- The cardiac conduction system is a primary focus of LD's cardiovascular effects.
- Further research is needed to fully understand the LD-heart relationship.
Conclusions:
- Lyme carditis (LC) is a significant complication of Lyme disease (LD).
- Understanding the diverse cardiac manifestations and management of LC is crucial.
- More research is required to elucidate the complex interactions between LD and cardiovascular health.
Abstract:
Lyme disease (LD) is an inflammatory disorder caused by an infectious bacterial agent and is the most common tick-borne illness in the United States and Europe. About 1.5-10% of adults infected with LD develop cardiac complications. This review summarizes the current knowledge of the epidemiology, pathophysiology, and diagnosis of Lyme carditis (LC), as well as the different manifestations of LD in the cardiovascular system. This review will primarily highlight the effect of LD on the cardiac conduction system and also discuss its effect on the myocardium, pericardium, valves, and coronary arteries. The management and prognosis of LC will be reviewed here as well. While this is a comprehensive review of the current literature on LC, there remain many questions regarding the complex relationship between LD and the heart.
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