Related Experiment Video
Updated: Jun 9, 2025

09:38
Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
Published on: April 14, 2016
12.6K
Summary
This article outlines key principles for assessing, diagnosing, and managing pain within neurologic practice. It emphasizes the evolving landscape of pain science and the neurologist
Area of Science:
- Neurology and Pain Management
- Neuroscience of Pain Perception
- Biopsychosocial Model of Pain
Background:
- Pain assessment and management are rapidly advancing fields.
- Diverse health professions contribute to pain research and practice.
- Transforming pain classification systems and diagnostic criteria.
Purpose of the Study:
- To introduce general principles for pain assessment in neurologic practice.
- To outline diagnostic approaches for pain conditions.
- To describe management strategies for pain relevant to neurology.
Main Methods:
- Review of current scientific understanding and clinical practices in pain.
- Integration of biopsychosocial model in pain assessment.
- Consideration of pharmacologic, non-pharmacologic, interventional, and surgical management.
Main Results:
- Pain perception is multifocal, involving various nervous system levels.
- Neurologists possess unique skills for evaluating and managing complex pain.
- Pain significantly impacts sleep, cognition, mobility, and social well-being.
Conclusions:
- Neurologists can optimize patient outcomes by applying expert knowledge and therapies.
- Interprofessional collaboration is crucial for effective pain management.
- The outlook for pain management is positive due to global collaboration and research funding.
Related Concept Videos
Analgesia and Pain Management
534
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
534
Pain
467
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
467
Nociception
27.7K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
27.7K
Opioid Analgesics: Synthetic and Semisynthetic Opioids
234
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
234
Peripheral Artery Disease V: Postoperative Nursing Management
3
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
3
Opioid Analgesics: Morphine and Other Natural Cogeners
187
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
187

