Supratentorial ependymomas. Neuroimaging and clinicopathological correlation

Area of Science:

• Neuro-oncology
• Neuroradiology
• Medical Imaging

Background:

• Supratentorial ependymomas are primary brain tumors.
• Accurate diagnosis and monitoring are essential for patient outcomes.

Purpose of the Study:

• To characterize the imaging features of supratentorial ependymomas on CT and angiography.
• To correlate imaging findings with tumor grade and patient prognosis.
• To establish optimal follow-up imaging protocols.

Main Methods:

• Retrospective analysis of CT scans and angiograms from 10 patients with supratentorial ependymomas.
• Comparison of imaging characteristics (e.g., density, enhancement, vascularity) with pathological tumor grade.
• Long-term follow-up using CT to assess tumor recurrence and clinical course.

Main Results:

• Tumors typically appeared hyperdense pre-contrast, with mixed cystic/necrotic components and calcifications.
• Moderate to marked contrast enhancement and mild hypervascularity were common.
• No correlation was found between imaging features and pathological anaplasia.
• Recurrence was frequent, particularly in high-grade tumors, highlighting the need for vigilant follow-up.

Conclusions:

• CT and angiography provide characteristic insights into supratentorial ependymomas.
• Imaging plays a vital role in assessing tumor behavior and guiding follow-up strategies.
• Recommended follow-up CT frequency: annually for low-grade and every 6 months for high-grade ependymomas.