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Author Spotlight: Polysome Profiling Protocol for Studying Translational Regulation in Arabidopsis Under Heat Stress
Published on: October 11, 2024
HIP is involved in NaCl and endoplasmic reticulum stress resistance in Arabidopsis
Kaiyue Zhang1, Meijie Duan2, Lele Shan2
1College of Life Sciences, Shandong Normal University, Jinan, 250014, Shandong, China; School of Life Sciences, Qilu Normal University, Jinan, 250200, China.
Abstract:
Heat shock protein 70 (HSP70)-interacting proteins (HIPs) have been studied in animals. HIPs perform diverse cellular functions, ranging from alleviating stress to suppressing the formation of insoluble protein, but how their orthologs function in plants is less known. This study shows that Arabidopsis HIP is a cytosolic and nuclear protein associated with HSP70. The hip mutants showed compromised tolerance to NaCl and endoplasmic reticulum (ER) stress, although they grew normally under standard growth conditions. Furthermore, hip mutants presented a decreased HSP70 level compared with the wild type under NaCl and ER stress conditions. These findings suggest the involvement of HIP in NaCl and ER stress tolerance.
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