Early prediction of sudden cardiac death using multimodal fusion of ECG Features extracted from Hilbert-Huang and

Hardik Telangore1, Victor Azad2, Manish Sharma1

  • 1Department of Electrical and Computer Science Engineering, Institute of Infrastructure, Technology, Research and Management (IITRAM), Ahmedabad, Gujarat, 380026, India; Centre of Advanced Defence Technology, Institute of Infrastructure, Technology, Research and Management (IITRAM), Ahmedabad, Gujarat, 380026, India.

Insights

This study introduces a deep learning model for early sudden cardiac death (SCD) prediction using electrocardiography (ECG) signals, achieving 98.81% accuracy up to 30 minutes prior to the event. The model offers a significant advancement for monitoring high-risk patients.

Area of Science:

  • Cardiology
  • Artificial Intelligence
  • Biomedical Signal Processing

Background:

  • Sudden cardiac death (SCD) is a critical health issue, often caused by ventricular fibrillation (VF).
  • Current SCD prediction methods offer limited intervention time, typically only minutes before onset.
  • Early prediction of SCD is crucial for timely interventions and improving patient outcomes.

Purpose of the Study:

  • To develop a deep learning-based model for early prediction of SCD using electrocardiography (ECG) signals.
  • To enhance the prediction window for SCD events, allowing for more effective interventions.
  • To utilize multimodal ECG signal analysis for improved SCD detection.

Main Methods:

  • A multimodal explainable deep learning model was developed to analyze ECG signals at 5- to 30-minute intervals before SCD onset.
  • Raw ECG, 2D scalograms (wavelet transform), and 2D Hilbert spectra (HHT) were processed using 1D-CNN, LSTM, Vision Transformer, and 2D-CNN.
  • The model integrated feature extraction and temporal pattern recognition for comprehensive ECG analysis.

Main Results:

  • The model achieved high performance with 98.81% accuracy, precision, recall, and F1-score for predicting SCD onset 30 minutes in advance.
  • The model demonstrated 100% accuracy in classifying SCD patients versus normal controls.
  • The developed method significantly outperforms existing state-of-the-art approaches in early SCD prediction.

Conclusions:

  • The deep learning model effectively captures diverse ECG patterns for discriminating SCD events up to 30 minutes prior.
  • This approach significantly improves early SCD prediction capabilities.
  • The model serves as a valuable tool for continuous ECG monitoring in high-risk individuals.
Abstract