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Updated: May 28, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
Published on: April 29, 2014
[Nephrectomy in a rabbit with renal adenocarcinoma]
Mona Engels1, Iria Dominguez Soutullo1
1Anicura Tiergesundheitszentrum Sankt Augustin, Sankt Augustin.
Abstract:
The following case report describes the clinical approach concerning diagnostic procedures and treatment of a renal adenocarcinoma in a 2-year-old rabbit presented due to hyporexia and polydipsia. The clinical examination disclosed an abdominal mass. Further imaging revealed a unilateral enlargement of the left kidney presumed to be of neoplastic origin. After staging via blood testing, abdominal ultrasound and radiographic imaging of the thorax and abdomen revealed no signs of metastasis, nephrectomy was performed. Patho-histological examination confirmed the diagnosis of a renal adenocarcinoma. Despite its guarded prognosis the patient recovered completely and was free of metastases or other health limitations 12 months after the surgery.

