Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Organ-Limited ANCA-Associated Orbital Inflammatory Disease: A Diagnostic Challenge.

Modern rheumatology case reports·2026

Same author

Rare fibroadenoma of the right upper eyelid arising from the tarsal plate.

Orbit (Amsterdam, Netherlands)·2026

Same author

Histiocytic Sarcoma of the Eyelid: An Uncommon Presentation of a Rare Neoplasm.

Ophthalmic plastic and reconstructive surgery·2026

Same author

Differentiating head and neck small-diameter lentigo maligna and lentigo maligna melanoma from challenging solar lentigines: A retrospective study.

Journal of the American Academy of Dermatology·2026

Same author

Authors' response to Mart et al's "Response to Navarrete-Dechent et al's 'Ultraviolet-induced fluorescent dermoscopy for the diagnosis of skin tumors: A multicenter study'".

Journal of the American Academy of Dermatology·2026

Same author

Spontaneous regression of a presumed orbitocranial eosinophilic granuloma in an adult patient: illustrative case.

Journal of neurosurgery. Case lessons·2026

Same journal

Highlights from JAAD Case Reports: September 2026: Repurposing established therapies through biologic insight.

Journal of the American Academy of Dermatology·2026

Same journal

First-Come, First-Served: Ethics of Coordinated Interview Releases.

Journal of the American Academy of Dermatology·2026

Same journal

Ethical Implications of Integrating Artificial Intelligence Tools into Dermatology Electronic Health Records.

Journal of the American Academy of Dermatology·2026

Same journal

Real-world experience with extended deucravacitinib-biologic combination therapy in refractory psoriasis and psoriatic arthritis.

Journal of the American Academy of Dermatology·2026

Same journal

Acute-phase Disease and Super-responder Status Predict Reduced Relapse Risk After Ritlecitinib Withdrawal in Alopecia Areata: A Prospective Real-World Study.

Journal of the American Academy of Dermatology·2026

Same journal

Response to Kvist-Hansen et al. 'Baseline monocytes ≥925/μL appear to represent a rare outlier phenotype rather than a generalizable predictor of adalimumab response in hidradenitis suppurativa.'

Journal of the American Academy of Dermatology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 9, 2025

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

Lentigo maligna part II: Management.

Sameer Gupta¹, Michael Shaughnessy², Sarem Rashid³

¹Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, Massachusetts.

Journal of the American Academy of Dermatology

|October 24, 2024

Summary

This summary is machine-generated.

Lentigo Maligna (LM), a skin cancer on sun-damaged skin, requires careful diagnosis and treatment. This review covers surgical and non-surgical options for managing LM, emphasizing cure and patient outcomes.

Keywords:

lentigo maligna melanoma nonsurgical management radiation therapy surgical management surveillance topical therapy

More Related Videos

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

Direct Reprogramming of Mouse Fibroblasts into Melanocytes

Direct Reprogramming of Mouse Fibroblasts into Melanocytes

Published on: August 27, 2021

Related Experiment Videos

Last Updated: Jun 9, 2025

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

Direct Reprogramming of Mouse Fibroblasts into Melanocytes

Direct Reprogramming of Mouse Fibroblasts into Melanocytes

Published on: August 27, 2021

Area of Science:

Dermatology
Oncology

Background:

Lentigo Maligna (LM) is a melanoma in situ common on chronically sun-exposed skin.
It can present with extensive subclinical spread, posing challenges in cosmetically and functionally sensitive areas.

Purpose of the Study:

To provide a comprehensive review of Lentigo Maligna (LM) in a two-part continuing medical education (CME) series.
To cover epidemiology, risk factors, diagnosis, histopathology, and treatment strategies for LM.

Main Methods:

Part I: Review of epidemiology, risk factors, clinical presentation, diagnostic tools, biopsy technique, and histopathology.
Part II: Review of surgical (excision, Mohs surgery, staged excision) and non-surgical (topical, radiation) treatment options.
Discussion of surveillance recommendations post-treatment.

Main Results:

Surgical interventions are the primary approach for achieving a cure for Lentigo Maligna.
Non-surgical modalities offer alternative treatment options for patients unsuitable for surgery or those who prefer them.
Effective management involves accurate diagnosis, appropriate treatment selection, and vigilant surveillance.

Conclusions:

Lentigo Maligna management necessitates a thorough understanding of its characteristics and available therapeutic modalities.
A multidisciplinary approach combining surgical and non-surgical options, tailored to individual patient needs, is crucial for optimal outcomes.
Long-term surveillance is essential to monitor for recurrence or new developments.