Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epistasis Analysis01:09

Epistasis Analysis

4.9K
Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...
4.9K
Ribosome Profiling02:24

Ribosome Profiling

3.5K
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
3.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

IL-6-induced C/EBPα drives follicular regulatory T cell differentiation to regulate humoral immunity in mice.

Nature communications·2026
Same author

Influence of Naturally Converted Nitrite and Ultrasound Marination on the Curing Efficiency and Residual Nitrite of Pork Loin.

Food science of animal resources·2026
Same author

Decoupling Moisture and Hydrogen Barrier Properties in Silicon Nitride Films Deposited by Plasma-Enhanced Atomic Layer Deposition at 100 °C via Precursor-Defined Bonding Networks.

ACS applied materials & interfaces·2026
Same author

Solvent-Dependent Biological Activities of Aqueous and Ethanolic Extracts From Edible Insect Larvae.

Food science & nutrition·2026
Same author

Strategies for replacing phosphates in meat processing.

Food science of animal resources·2026
Same author

Effects of Natural Extract Mixtures on the Quality Characteristics of Sausages during Refrigerated Storage.

Food science of animal resources·2026

Related Experiment Video

Updated: Jun 9, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
08:27

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

3.5K

A brief guide to analyzing expression quantitative trait loci.

Byung Su Ko1, Sung Bae Lee1, Tae-Kyung Kim2

  • 1Department of Brain Sciences, DGIST, Daegu 42988, Republic of Korea.

Molecules and Cells
|October 24, 2024
PubMed
Summary
This summary is machine-generated.

This study offers a guide to molecular quantitative trait locus (molQTL) mapping, focusing on expression quantitative trait loci (eQTLs). It simplifies complex analysis tools for researchers studying genetic variants and complex traits.

More Related Videos

QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii
11:37

QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii

Published on: June 22, 2017

16.2K
An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
10:17

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

22.8K

Related Experiment Videos

Last Updated: Jun 9, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
08:27

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

3.5K
QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii
11:37

QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii

Published on: June 22, 2017

16.2K
An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
10:17

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

22.8K

Area of Science:

  • Genetics
  • Bioinformatics
  • Systems Biology

Background:

  • Molecular quantitative trait locus (molQTL) mapping is crucial for understanding genetic variant functions and disease mechanisms.
  • The complexity of available analysis tools poses a challenge for researchers, especially those with limited computational expertise.

Purpose of the Study:

  • To provide a concise guideline for molecular quantitative trait locus (molQTL) analysis.
  • To curate a list of methods and software tools specifically for expression quantitative trait loci (eQTL) studies.

Main Methods:

  • Literature review and curation of existing molQTL analysis tools.
  • Categorization of methods based on their application in eQTL studies.

Main Results:

  • A structured overview of prevalent molQTL mapping methodologies.
  • A curated list of user-friendly software tools for expression quantitative trait loci (eQTL) analysis.

Conclusions:

  • This guideline aims to demystify molQTL analysis for a broader research audience.
  • Facilitating the study of genetic influences on gene expression and complex traits through accessible computational tools.