Related Experiment Video
Updated: Jun 9, 2025
07:29
Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
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Keratoconus
Rohan Bir Singh1,2, Shizuka Koh3, Namrata Sharma4
1Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Nature Reviews. Disease Primers
|October 25, 2024
Summary
Keratoconus is a progressive corneal disorder affecting young adults, causing vision loss. Early detection and treatments like corneal cross-linking can manage its progression.
Area of Science:
- Ophthalmology
- Corneal Diseases
- Vision Science
Background:
- Keratoconus is a progressive corneal ectasia affecting adolescents and young adults.
- It leads to corneal thinning, steepening, irregular astigmatism, and vision reduction.
- Its etiology involves genetic, environmental, biomechanical, and cellular factors.
Purpose of the Study:
- To provide a comprehensive overview of keratoconus.
- To discuss its complex etiology and pathogenesis.
- To outline current diagnostic and therapeutic strategies.
Main Methods:
- Clinical examination and advanced corneal imaging for diagnosis.
- Assessment of disease severity and progression for treatment tailoring.
- Review of established and emerging treatment modalities.
Main Results:
- Early diagnosis is enhanced by advanced imaging platforms.
- Treatment ranges from refractive correction to surgical interventions.
- Corneal cross-linking is a key treatment to halt disease progression.
Conclusions:
- Keratoconus management requires a multifaceted approach.
- Early intervention and appropriate treatments are crucial for preserving vision.
- Ongoing research continues to refine understanding and treatment of keratoconus.
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