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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Efficient feature selection for histopathological image classification with improved multi-objective WOA.

Ravi Sharma1, Kapil Sharma2, Manju Bala3

  • 1Delhi Technological University, Bawana, New Delhi, 110042, India. ravisrma1988@gmail.com.

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|October 25, 2024
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Summary
This summary is machine-generated.

This study introduces an enhanced multi-objective whale optimization algorithm for efficient feature selection in histopathology image analysis, improving accuracy and reducing computation time compared to existing methods.

Keywords:
Image classificationMulti-objective grey wolf optimizerOptimization algorithmPre processing

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Area of Science:

  • Computational pathology
  • Bioinformatics
  • Machine learning

Background:

  • Efficient feature selection is critical for histopathology image analysis but remains a challenge.
  • Current methods often treat feature selection as a single-objective problem, limiting their effectiveness.

Purpose of the Study:

  • To propose an enhanced multi-objective whale optimization algorithm (EMOWOA) for feature selection in histopathology.
  • To address the limitations of single-objective approaches in complex image analysis tasks.

Main Methods:

  • Developed and utilized an enhanced multi-objective whale optimization algorithm (EMOWOA).
  • Validated EMOWOA on 10 standard multi-objective benchmark functions (CEC2009).
  • Compared EMOWOA against three existing feature selection techniques using five classifiers, evaluating accuracy, selected features, and computation time.

Main Results:

  • The proposed EMOWOA demonstrated superior optimization capabilities on benchmark functions.
  • EMOWOA significantly outperformed existing methods across evaluated parameters (accuracy, feature count, time).
  • The algorithm effectively mines optimal feature sets for histopathology image analysis.

Conclusions:

  • The enhanced multi-objective whale optimization algorithm offers a robust solution for efficient feature selection in histopathology.
  • This approach improves upon traditional single-objective methods, providing better performance metrics.
  • The findings highlight the potential of multi-objective optimization for advancing computational pathology.