Prostatic carcinoma: 5-year followup of patients with surgically staged disease undergoing extended field radiation

We analyzed all patients who had undergone pre-radiation staging pelvic lympadenectomy from 1969 to 1979. Of 70 patients with a minimum followup of 5 years 33 had positive and 37 had negative nodes. Three of the 33 patients with positive lymph nodes were alive without disease at the time of our study, compared to 20 of 37 with negative lymph nodes. Our review suggests that extended field radiation has minimal or no impact on the natural history of prostatic carcinoma in patients with positive nodes. Patients with stages T1 and T2 lesions, and negative nodes do well with external beam therapy.