Related Experiment Video

Updated: Jun 9, 2025

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
07:51

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

7.6K

Lowering the risk of hyperuricemia and gout is associated with ideal cardiovascular health

Pengfei Liu1, Kaisaierjiang Kadier2, Chunying Cui3

  • 1Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

Journal of Health, Population, and Nutrition
|October 25, 2024
PubMed

Insights

Maintaining ideal cardiovascular health (CVH) is linked to lower rates of hyperuricemia (HUA) and gout. This study found that higher Life's Essentials 8 (LE8) scores were associated with reduced prevalence of these conditions in US adults.

Area of Science:

  • Cardiovascular Health
  • Metabolic Diseases
  • Public Health

Background:

  • Hyperuricemia (HUA) and gout are independent cardiovascular disease risk factors.
  • The association between ideal cardiovascular health (CVH) and HUA/gout is not well-established.
  • Life's Essentials 8 (LE8) is a recent metric for assessing ideal CVH.

Purpose of the Study:

  • To investigate the relationship between CVH, measured by LE8, and the prevalence of HUA and gout.
  • To analyze this association in a nationally representative sample of US adults.

Main Methods:

  • Cross-sectional analysis of National Health and Nutrition Examination Survey (NHANES) data (2007-2018).
  • CVH components defined by American Heart Association guidelines.
  • Weighted multivariable logistic and restricted cubic spline (RCS) models used to assess associations.

Main Results:

  • Prevalence of HUA was 17.20% and gout was 3.58% in 21,155 adults.
  • Higher LE8 scores significantly correlated with lower odds of HUA (OR 0.25 for high CVH) and gout (OR 0.32 for high CVH).
  • Nonlinear negative association between LE8 score and HUA; linear negative correlation with gout.

Conclusions:

  • A significant negative correlation exists between LE8 score and HUA/gout prevalence.
  • Achieving ideal CVH may reduce the burden of HUA and gout.
Abstract

Keywords:
Cardiovascular healthGoutHyperuricemiaLife’s essential 8NHANES

More Related Videos

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles09:15

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

14.6K
Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia11:06

Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia

Published on: April 7, 2023

1.9K

Related Concept Videos

Coronary Artery Disease IV: Medical Management01:26

Coronary Artery Disease IV: Medical Management

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
3
Lipid-Lowering Drugs: Statins and Miscellaneous Agents01:20

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
558
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
1
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
2
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
741
Antihypertensive Drugs: Action of Diuretics01:16

Antihypertensive Drugs: Action of Diuretics

Diuretics are antihypertensive drugs used to treat hypertension resulting from sodium and water retention. Sodium, vital for fluid balance and nerve or muscle function, is regulated by the kidneys through millions of nephrons. Blood enters nephrons via afferent arterioles, which branch into capillaries called glomeruli. These filter blood plasma, allowing water and solutes, like sodium ions, to pass through capillary walls into Bowman's capsule. The filtrate then flows through various...
624