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Published on: May 5, 2020
Acute Onset of Peripheral Facial Nerve Palsy in Children: An Overview
Virginia Fancello1, Andrea Ciorba2, Daniele Monzani3
1Otolaryngology Division, Azienda Ospedaliero Universitaria Sassari, 07100 Sassari, Italy.
Insights
Pediatric facial nerve palsy often has no clear cause but usually resolves. Infections like Lyme disease and herpesviruses are common triggers, with recovery rates generally high for children.
Area of Science:
- Neurology
- Pediatrics
- Otolaryngology
Background:
- The facial nerve (FN) is crucial for facial muscle innervation, emotional expression, and non-verbal communication.
- Dysfunction, particularly in childhood, significantly impacts quality of life.
- Peripheral facial nerve palsy (FNP) in children requires understanding of causes and treatments.
Purpose of the Study:
- To review recent literature on acute peripheral facial nerve palsy in pediatric patients.
- To analyze etiologies, prognoses, and management strategies for childhood FNP.
- To synthesize data from existing studies on pediatric FNP.
Main Methods:
- Systematic review of literature focusing on pediatric peripheral FNP.
- Initial search identified 882 papers; 7 met selection criteria.
- Data from 974 children were pooled and analyzed.
Main Results:
- Idiopathic causes predominated in pediatric FNP.
- Infective etiologies were the second most common, with Borrelia Burgdorferi and Herpesviridae identified.
- Respiratory/ear infections and trauma were less frequent causes.
Conclusions:
- High overall recovery rates for pediatric facial nerve palsy are observed.
- Etiology remains unknown in a significant number of cases.
- Evidence-based therapeutic guidelines are needed, especially for persistent FNP.
Abstract:
Background The facial nerve (FN) plays a pivotal role in human life; apart from its sensory and parasympathetic functions, it innervates the facial muscles, and it is therefore involved in non-verbal communication, allowing us to express emotions and reactions. Especially in the case of childhood onset, FN dysfunction can severely affect the quality of life. Methods The aim of this review is to analyze the most recent literature, focusing on the acute onset of peripheral FN palsy among pediatric patients, discussing the different etiologies, prognoses, and management strategies. A total of 882 papers were initially identified, but only 7 met the selection criteria. Therefore, data on 974 children in total were pooled and analyzed. Results According to the findings of this review, FN palsy is idiopathic in most cases, while an infective etiology was identified as the second most common. The main pathogen agents identified were Borrelia Burgdorferi, especially in endemic areas, and Herpesviridae. Respiratory tract infections and/or ear infections were also described. Head trauma or direct injury of the FN accounted for 2% of all cases. Conclusions The overall FN recovery rate is high, even though the etiology remains unknown for most patients. Therapeutic indications are still lacking, especially in the case of non-recovering FN palsy. In our opinion, large, prospective studies are necessary for improving our knowledge of this disorder and establishing evidence-based approaches.
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