Unraveling the Obesity Paradox: Exploring the Impact of Body Weight on Cutaneous Melanoma Prognosis in Asian Population
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View abstract on PubMed
Summary
This summary is machine-generated.Obesity may be a protective factor for melanoma patients in Taiwan. This study found that individuals with obesity had better survival rates compared to normal or underweight individuals, challenging previous assumptions.
Area Of Science
- Oncology
- Dermatology
- Epidemiology
Background
- Obesity is a known risk factor for many diseases, but its link to melanoma prognosis is debated.
- Cutaneous melanoma incidence is rising in Taiwan, yet research on obesity's role is limited.
Purpose Of The Study
- To investigate the association between obesity and the prognosis of cutaneous melanoma in Taiwan.
- To determine if body weight impacts survival rates in melanoma patients.
Main Methods
- Retrospective analysis of 201 cutaneous melanoma patients diagnosed between 2000 and 2022.
- Data collected included body weight, height, tumor stage, and patient prognosis.
- Statistical analysis was performed to identify risk and protective factors for survival.
Main Results
- Older age, male sex, advanced tumor stage (T3-T4), and ulceration were associated with worse survival.
- Being overweight was identified as a protective factor for both cutaneous and acral melanoma.
- Obese melanoma patients demonstrated better survival rates than normal or underweight patients.
Conclusions
- Contrary to expectations, obesity appears to be associated with improved survival in melanoma patients.
- No significant difference in the effect of body weight on survival was observed between acral and non-acral melanoma subtypes.
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