Related Experiment Video
Updated: Jun 9, 2025

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
Published on: September 30, 2020
Prevalence of clinical deterioration in the pre-hospital setting
Emma Bourke-Matas1,2, Tan Doan2,3, Kelly-Ann Bowles1
1Department of Paramedicine, School of Primary and Allied Health Care, Monash University, Melbourne, Victoria, Australia.
Insights
Pre-hospital clinical deterioration and adverse events (AEs) were found to be low. However, nearly half of patients with AEs did not meet early warning score thresholds, indicating a need for better detection methods.
Area of Science:
- Emergency Medicine
- Pre-hospital Care
- Patient Safety
Background:
- Early recognition of patient deterioration in pre-hospital settings is crucial for timely intervention.
- Undetected deterioration can lead to profound negative outcomes.
- Understanding the prevalence of pre-hospital clinical deterioration is essential.
Purpose of the Study:
- To investigate the prevalence of pre-hospital clinical deterioration.
- To determine the incidence of adverse events (AEs) within three days of pre-hospital care.
- To identify patient characteristics associated with AEs.
Main Methods:
- Retrospective cohort study of adult patients attended by Queensland Ambulance Service (2018-2020).
- Utilized early warning scores (NEWS, MEWS, Q-ADDS) to identify clinical deterioration from vital signs.
- Linked hospital data to identify adverse events.
Main Results:
- Pre-hospital clinical deterioration observed in 2.7%-4% of patients.
- Prevalence of adverse events (AEs) was 3.2%.
- Nearly 50% of patients experiencing AEs did not meet established early warning score thresholds.
Conclusions:
- The prevalence of pre-hospital clinical deterioration and subsequent AEs is low.
- Standardized criteria are needed for defining pre-hospital clinical deterioration.
- Further research should evaluate the performance of early warning scores in this setting.
Objective:
Improved understanding of the deteriorating patient in the pre-hospital setting may result in earlier recognition and response. Considering the effects of undetected deterioration are profound, it is fundamental to report the prevalence of pre-hospital clinical deterioration to advance our understanding. The present study investigated the prevalence of pre-hospital clinical deterioration and adverse events (AEs) within 3 days of the pre-hospital episode of care.
Methods:
This retrospective cohort study was based on pre-hospital incidents involving adult patients attended by Queensland Ambulance Service between 1 January 2018 and 31 December 2020. Due to lacking a standardised definition of pre-hospital clinical deterioration, established early warning scores (NEWS, MEWS and Q-ADDS) were calculated from pre-hospital vital signs to identify clinical deterioration. Linked hospital data were used to identify the occurrence of an AE.
Results:
Some degree of physiological derangement was initially observed in over half of the patients, and pre-hospital clinical deterioration was seen in 2.7%-4% of patients. The prevalence of AEs was 3.2%. Patients that experienced an AE were more likely to be male, elderly, suffering from a medical (non-trauma) condition, and had a greater burden of disease. Concerningly, almost 50% of patients that suffered an AE did not meet escalation thresholds of NEWS, MEWS or Q-ADDS.
Conclusions:
The present study found the prevalence of pre-hospital clinical deterioration and AEs subsequent to pre-hospital episodes of care to be low. Future research should prioritise using standardised criteria to define pre-hospital clinical deterioration and evaluate the performance of early warning scores.
Related Concept Videos
Heart Failure III: Clinical Manifestations
Pulmonary Embolism I: Introduction
Acute Respiratory Failure-IV
Introduction Cardiac Emergencies
Coronary Artery Disease III: Clinical Manifestations
Acute Coronary Syndrome IV: Interprofessional Care

