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Psychological Distress Is Prevalent and Interdependent Among Patients With Decompensated Cirrhosis and Their
Nneka N Ufere1, Chengbo Zeng2, John Donlan3
1Liver Center, Gastrointestinal Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Introduction:
Little is known about the interdependence of psychological distress among patients with decompensated cirrhosis and their caregivers.
Methods:
In this cross-sectional study, we examined the interdependence of psychological distress (Hospital Anxiety and Depression Scale) among 127 patient-caregiver dyads using Actor-Partner Interdependence Modeling.
Results:
Among dyads, 26% had both partners reporting clinically significant anxiety and 18% reporting clinically significant depression. Caregiver anxiety significantly predicted patient depression (standardized β = 0.18, P = 0.03).
Discussion:
Psychological distress was prevalent and interdependent among dyads. These results underscore the need to develop interventions to reduce psychological distress in both patients with decompensated cirrhosis and their caregivers.
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