Related Experiment Video
Updated: Jun 9, 2025

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
COMPLICATED CARDIAC ARREST AND ITS RESUSCITATION CHARACTERISTICS IN PATIENTS WITH INTRACEREBRAL HEMORRHAGE: CHINESE
Ping Lu1, Lingyun Cui1, Hongqiu Gu2
1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Insights
Cardiac arrest in intracerebral hemorrhage patients is influenced by emergency medical services notification and post-hospital complications like hematoma expansion. Survival rates improved annually from 2015-2019.
Area of Science:
- Neurology
- Emergency Medicine
- Critical Care Medicine
Background:
- Cardiac arrest (CA) is a severe complication in patients with intracerebral hemorrhage (ICH).
- ICH-related CA significantly increases the risk of mortality.
- Understanding factors influencing CA and resuscitation is crucial for improving patient outcomes.
Purpose of the Study:
- To explore factors influencing cardiac arrest occurrence in intracerebral hemorrhage patients.
- To investigate resuscitation characteristics and outcomes in ICH patients experiencing CA.
- To identify predictors of CA and mortality in this patient population.
Main Methods:
- Retrospective analysis of data from the Chinese Stroke Center Alliance database.
- Inclusion of 85,105 patients with intracerebral hemorrhage.
- Logistic regression analysis to identify co-factors influencing CA and mortality.
Main Results:
- 1.9% of ICH patients experienced cardiac arrest, with a 62.5% in-hospital mortality rate.
- Prehospital emergency medical service notification was associated with both CA occurrence and mortality.
- Posthospital hematoma expansion and swallowing dysfunction were significant co-factors for CA and death.
Conclusions:
- Prehospital notification, hematoma expansion, and swallowing dysfunction are key co-factors for CA and mortality in ICH.
- The incidence of CA in ICH patients decreased annually from 2015 to 2019.
- Survival rates following CA in ICH patients showed a significant annual improvement during the study period.
Abstract:
Objective: Cardiac arrest (CA) is one of the most severe complications in patients with intracerebral hemorrhage (ICH), increasing the risk of death. This study explored the factors influencing CA occurrence and its resuscitation characteristics in ICH patients. Methods: Data were retrieved from the Chinese Stroke Center Alliance database. The primary outcome was CA, and the secondary outcomes were in-hospital death and survival post- CA. Absolute standardized and rate differences were utilized for intergroup comparisons, while logistic regression was employed for correlation analysis. Results: A total of 85,105 patients were enrolled in this study. Among them, 1651 (1.9%) patients experienced CA, of whom 1032 (62.5%) died in hospital. At baseline, prehospital notification from the emergency medical service system was a co-factor influencing CA occurrence and the presence of a death outcome (OR: 1.71, 95% CI: 1.47-1.98, P < 0.001; OR: 0.50, 95% CI: 0.41-0.62, P < 0.001). In terms of complications, posthospital hematoma expansion and swallowing dysfunction were co-factors influencing CA occurrence and the presence of a death outcome (OR: 3.78, 95% CI: 3.20-4.47, P < 0.001, OR: 1.39, 95% CI: 1.11-1.76; P < 0.001; OR: 7.66, 95% CI: 5.48-10.70, P < 0.001, OR: 1.66, 95% CI: 1.08-2.57, P < 0.001). The incidence of CA in ICH patients decreased annually from 2015 to 2019, while survival after CA increased annually ( P < 0.001). Conclusions: Prehospital notification from the emergency medical service system, posthospital hematoma expansion, and swallowing dysfunction were identified as co-factors contributing to CA occurrence and post-CA mortality following ICH. The proportion of CA patients following ICH decreased, while survival rates improved annually from 2015 to 2019.
Related Concept Videos
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiopulmonary Resuscitation I: Adult
Cardiopulmonary Resuscitation III: AED Use

