Related Experiment Video

Updated: Jun 9, 2025

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.3K

Impact of Psoas Muscle Area Index on Short- and Mid-Term Mortality in Patients Undergoing Valve Surgery for Infective

Christian Dinges1, Matthias Hammerer2, Nikolaos Schörghofer3

  • 1Department of Cardiovascular and Endovascular Surgery, Paracelsus Medical University of Salzburg, 5020 Salzburg, Austria.

Diagnostics (Basel, Switzerland)
|October 25, 2024
PubMed

Insights

Sarcopenia, or loss of skeletal muscle mass, predicts higher mortality after valve surgery for infective endocarditis. Assessing sarcopenia using Psoas muscle area index (PMAi) can improve risk stratification for these high-risk patients.

Area of Science:

  • Cardiology
  • Geriatrics
  • Surgical Outcomes

Background:

  • Sarcopenia is an emerging comorbidity in cardiovascular surgery.
  • Its impact on mortality in infective endocarditis (IE) valve surgery patients is underexplored.

Purpose of the Study:

  • To investigate the relationship between sarcopenia, measured by Psoas muscle area index (PMAi), and mortality in IE patients undergoing valve surgery.

Main Methods:

  • Retrospective analysis of 68 IE patients undergoing valve surgery (2013-2021).
  • Sarcopenia defined by lowest quartile of preoperative PMAi (CT scan).
  • Kaplan-Meier curves, Cox regression, and ROC curves analyzed survival and predictors.

Main Results:

  • Sarcopenia strongly associated with increased 1-year (HR: 0.378) and 3-year (HR: 0.457) mortality.
  • Female sex and older age predicted sarcopenia.
  • Chronic kidney insufficiency and heart failure medication impacted survival.

Conclusions:

  • Sarcopenia is an independent predictor of short- and mid-term mortality in IE valve surgery patients.
  • Routine radiological assessment of sarcopenia (PMAi) can enhance risk stratification.
  • Tailored interventions for older women and patients with CKI may improve outcomes.
Keywords:
computed tomographyendocarditispsoas muscle area indexsarcopeniavalve surgery

More Related Videos

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

1.5K
Posterior Approach for Debridement of the Psoas Abscess06:02

Posterior Approach for Debridement of the Psoas Abscess

Published on: March 2, 2020

10.8K

Related Concept Videos

Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
2
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
2
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
3
Coronary Artery Disease V: Surgical Management01:27

Coronary Artery Disease V: Surgical Management

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
3
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
4
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
174