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Related Experiment Video

Updated: Jun 9, 2025

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting
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Needle Tip Tracking through Photoluminescence for Minimally Invasive Surgery.

Meenakshi Narayan1, Mithun Bhowmick2

  • 1Department of Engineering Technology, Miami University, Middletown, OH 45042, USA.

Biosensors
|October 25, 2024
PubMed
Summary
This summary is machine-generated.

This study introduces an all-optical method for tracking surgical needles using fluorescent markers in simulated tissues. This technique enhances minimally invasive surgery safety and shows potential for robot-assisted procedures.

Keywords:
biosensorsfluorescent markersminimally invasive surgeryneedle tip trackingphotoluminescence

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Area of Science:

  • Biomedical Engineering
  • Optical Imaging
  • Surgical Technology

Background:

  • Minimally invasive surgery (MIS) relies on advanced imaging for safety.
  • Current techniques often involve complex imaging equipment.
  • There is a need for simpler, optical-based tracking methods in MIS.

Purpose of the Study:

  • To explore an all-optical alternative for tracking surgical needles in simulated tissues.
  • To evaluate fluorescent markers for real-time needle tip localization.
  • To assess tissue characterization capabilities using photoluminescence.

Main Methods:

  • Investigated inorganic (Perovskite, PbS) and organic (carbon dots, Rhodamine 6G) fluorescent nanoparticles.
  • Utilized Rhodamine 6G dye for its high fluorescence signal.
  • Tracked a surgical needle within homogeneous and inhomogeneous gelatin tissue models.

Main Results:

  • Successfully tracked a surgical needle's 3D position in simulated tissues.
  • Demonstrated the potential of fluorescent markers for identifying tissue layers of varying stiffness.
  • Rhodamine 6G proved effective for needle tracking due to its strong fluorescence.

Conclusions:

  • An all-optical photoluminescence technique shows promise for in vitro needle tracking.
  • This method can enhance safety and real-time feedback in minimally invasive procedures.
  • Potential for future application in robot-assisted needle insertions during in vivo surgeries.