Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

New Advances in Neuroimmunology and Neuroinflammation.

Brain sciences·2026
Same author

Diagnostic Genetic Findings From Exome Sequencing in a Cohort of 1,109 Children With Epilepsy.

Neurology. Genetics·2026
Same author

An X-linked long non-coding RNA, PTCHD1-AS, and the core features of autism.

Nature·2026
Same author

Emerging Roles, Mechanisms, and Therapeutic Potential of Thyroid Hormones in Neurodegenerative Diseases: A Review.

Brain sciences·2026
Same author

Effects of Thyroid Hormones on Brain Development: Cytoarchitecture and Neurodevelopmental Disorders.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026
Same author

Dysfunctional circular RNA network in major depressive disorder: dissecting the cell identity and potential clinical applications.

Molecular psychiatry·2025
Same journal

Anterior Cingulate Cortex Mediates State-Dependent Prioritization of Distressed Conspecifics.

Brain sciences·2026
Same journal

Hemispherotomy for Pediatric Post-Traumatic Epilepsy.

Brain sciences·2026
Same journal

When Robots Learn: Artificial Intelligence and the Next Human-Centered Era of Neurorehabilitation.

Brain sciences·2026
Same journal

The Association Between Changes in White Matter Microstructure and Cognitive Function in Older Adults with Mild Cognitive Impairment.

Brain sciences·2026
Same journal

Beyond Ventricular Enlargement: Multimodal MRI Assessment Improves Surgical Decision-Making in Normal Pressure Hydrocephalus.

Brain sciences·2026
Same journal

The Effects of Personalized Observation, Execution, and Mental Imagery (POEM) Therapy in Logopenic Primary Progressive Aphasia: A Telepractice-Based Single-Case Study.

Brain sciences·2026
See all related articles

Related Experiment Video

Updated: May 13, 2026

Detection of MicroRNAs in Microglia by Real-time PCR in Normal CNS and During Neuroinflammation
13:36

Detection of MicroRNAs in Microglia by Real-time PCR in Normal CNS and During Neuroinflammation

Published on: July 23, 2012

19.4K

Advances in Neuroinflammation.

Junhui Wang1,2, Jing Sun3, Hongxing Wang4

  • 1Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada.

Brain Sciences
|October 25, 2024
PubMed
Summary
This summary is machine-generated.

Neuroinflammation research reveals its critical role in neurological diseases. Understanding these mechanisms is key to developing treatments for neurodegenerative conditions.

More Related Videos

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

14.6K
Brain Ventricular Microinjections of Lipopolysaccharide into Larval Zebrafish to Assess Neuroinflammation and Neurotoxicity
07:31

Brain Ventricular Microinjections of Lipopolysaccharide into Larval Zebrafish to Assess Neuroinflammation and Neurotoxicity

Published on: August 23, 2022

3.1K

Related Experiment Videos

Last Updated: May 13, 2026

Detection of MicroRNAs in Microglia by Real-time PCR in Normal CNS and During Neuroinflammation
13:36

Detection of MicroRNAs in Microglia by Real-time PCR in Normal CNS and During Neuroinflammation

Published on: July 23, 2012

19.4K
Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

14.6K
Brain Ventricular Microinjections of Lipopolysaccharide into Larval Zebrafish to Assess Neuroinflammation and Neurotoxicity
07:31

Brain Ventricular Microinjections of Lipopolysaccharide into Larval Zebrafish to Assess Neuroinflammation and Neurotoxicity

Published on: August 23, 2022

3.1K

Area of Science:

  • Neuroscience
  • Immunology

Background:

  • Neuroinflammation is increasingly recognized as a central factor in the pathogenesis of various neurological disorders.
  • Significant research efforts are focused on elucidating the complex interplay between the immune system and the central nervous system.

Discussion:

  • The abstract highlights the growing body of evidence linking neuroinflammation to the progression of neurodegenerative diseases.
  • Key areas of investigation include identifying specific inflammatory pathways and cellular players involved.

Key Insights:

  • Neuroinflammation plays a pivotal role in the development and exacerbation of neurodegenerative conditions.
  • Advanced research is uncovering the molecular mechanisms underlying neuroinflammation in disease contexts.

Outlook:

  • Future research aims to translate these findings into targeted therapeutic strategies for neurological diseases.
  • Developing effective treatments for neurodegenerative disorders may hinge on modulating neuroinflammatory responses.