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Infection01:20

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Refinements in Clinical and Behavioral Management for Macaques on Infectious Disease Protocols.

Lauren Drew Martin1, Jaclyn Shelton1, Lisa A Houser1

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Veterinary Sciences
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Summary

Improving animal welfare for research macaques involves enhancing clinical and behavioral care. Refinements like social housing and positive reinforcement training are key for nonhuman primates (NHPs) in infectious disease studies.

Keywords:
SIVpositive reinforcement trainingprocedure cagesocial housing

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Area of Science:

  • Veterinary Science
  • Animal Behavior
  • Primate Research

Background:

  • Optimal clinical and behavioral care is crucial for animal welfare in research settings.
  • Nonhuman primates (NHPs), especially macaques, on infectious disease protocols present unique management challenges.
  • Traditional single housing for NHPs can lead to adverse behavioral and clinical outcomes.

Purpose of the Study:

  • To review advancements in clinical and behavioral management for macaques in infectious disease studies.
  • To highlight refinements that improve the welfare of research NHPs.
  • To discuss the implementation and logistical considerations of these welfare improvements.

Main Methods:

  • Review of current literature and practices in NHP welfare.
  • Examination of specific welfare-enhancing techniques for macaques.
  • Analysis of strategies for facilitating the adoption of improved management practices.

Main Results:

  • Increased social housing positively impacts NHP welfare.
  • Positive reinforcement training facilitates cooperation with procedures like injections and blood draws.
  • Implementation strategies and logistical factors for refinements are discussed.

Conclusions:

  • Refinements in housing and training significantly improve clinical and behavioral care for research macaques.
  • Facilitating the implementation of these techniques is essential for advancing NHP welfare.
  • Continued efforts are needed to further enhance the welfare of NHPs in research.