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Clinical Course of Coronavirus disease 2019 C-19 in Patients with Bronchiectasis

Ebru Çakır Edis1, Aykut Çilli2, Deniz Kızılırmak3

  • 1Department of Pulmoner Medicine, Trakya University Faculty of Medicine, Edirne, Türkiye.

Thoracic Research and Practice
|October 25, 2024
PubMed

Insights

Patients with severe bronchiectasis, especially cystic types, are more likely to develop COVID-19. However, these factors do not predict the infection's severity in bronchiectasis patients.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Epidemiology

Background:

  • Coronavirus disease 2019 (COVID-19) poses a global health challenge, with increased severity noted in individuals with chronic lung conditions.
  • Limited data exists on COVID-19 outcomes specifically in patients diagnosed with bronchiectasis.

Purpose of the Study:

  • To investigate the clinical course of COVID-19 in patients with bronchiectasis.
  • To identify factors influencing the clinical outcomes of COVID-19 in this patient group.

Main Methods:

  • Utilized data from the Turkish Adult Bronchiectasis Database (TEBVEB), a multi-center registry.
  • Analyzed COVID-19 related data for 606 patients with bronchiectasis between March 2019 and January 2022.

Main Results:

  • 119 (19.6%) bronchiectasis patients contracted COVID-19, often presenting with comorbidities, cystic bronchiectasis, and higher Bronchiectasis Severity Index scores.
  • Most COVID-19 patients (68.9%) were managed as outpatients, with fewer requiring inpatient (22.7%) or intensive care unit (8.4%) admission.
  • While older age and male sex showed a trend towards hospitalization, these did not reach statistical significance.

Conclusions:

  • Severe bronchiectasis, cystic bronchiectasis, and a worse Bronchiectasis Severity Index are associated with an increased risk of developing COVID-19.
  • These specific bronchiectasis characteristics do not appear to correlate with the severity of the COVID-19 infection itself.
Abstract

Keywords:
COVID-19bronchiectasisdisease severity

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