Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deconvolution approaches for energy-preserving spatiotemporal cavitation dosimetry using passive acoustic mapping.

Ultrasonics·2026
Same author

Physiology of everyday sleep and physical activity: An exploratory mixed-methods study of multi-sensor wearables for infants and toddlers.

Behavior research methods·2026
Same author

Fisetin-loaded Nanoemulsion and Fecal Microbiome Extract Enhance In Vitro Inhibition of Non-Small Cell Lung Cancer Progression.

Cell biochemistry and biophysics·2026
Same author

Cystic fibrosis newborn screening in a high prevalence population - Ten years' experience in Ireland.

Respiratory medicine·2025
Same author

Implementation Timeframes for the Addition of New Conditions to Newborn Bloodspot Screening Programmes: A Scoping Review.

International journal of neonatal screening·2025
Same author

Identification of Drug Repurposing Candidates for Coxsackievirus B3 Infection in iPSC-Derived Brain-like Endothelial Cells.

International journal of molecular sciences·2025

Related Experiment Video

Updated: Jun 9, 2025

Author Spotlight: Using Zebrafish to Explore Microglia Migration During Brain Development
07:45

Author Spotlight: Using Zebrafish to Explore Microglia Migration During Brain Development

Published on: May 17, 2024

1.1K

Zebrafish as a Model for Multiple Sclerosis.

Briana Maktabi1, Abigail Collins2, Raihaanah Safee3

  • 1Department of Pharmacology and Experimental Therapeutics, University of Toledo, Toledo, OH 43614, USA.

Biomedicines
|October 26, 2024
PubMed
Summary

Zebrafish models offer valuable insights into multiple sclerosis (MS) pathology, aiding the study of demyelination and remyelination. Continued research using these models is crucial for developing effective MS treatments.

Keywords:
in vitroin vivomultiple sclerosisneurodegenerativezebrafish

More Related Videos

In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

20.7K
Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain
10:01

Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain

Published on: October 25, 2017

11.2K

Related Experiment Videos

Last Updated: Jun 9, 2025

Author Spotlight: Using Zebrafish to Explore Microglia Migration During Brain Development
07:45

Author Spotlight: Using Zebrafish to Explore Microglia Migration During Brain Development

Published on: May 17, 2024

1.1K
In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

20.7K
Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain
10:01

Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain

Published on: October 25, 2017

11.2K

Area of Science:

  • Neuroscience
  • Immunology
  • Genetics

Background:

  • Zebrafish are increasingly utilized as a model organism in neuroscience research due to their genetic, anatomical, and physiological similarities to humans.
  • Their rapid development and transparent embryos facilitate the study of neurobiology and neurological disorders.
  • Multiple sclerosis (MS), a chronic autoimmune disease damaging the myelin sheath, is a key focus of zebrafish research.

Purpose of the Study:

  • To review the significance of zebrafish in understanding multiple sclerosis (MS) pathology.
  • To highlight the importance of in vitro and in vivo models for MS research.
  • To emphasize the need for continued investigation to improve treatments and patient quality of life.

Main Methods:

  • Review of recent studies utilizing zebrafish as a model organism.
  • Investigation of demyelination and remyelination processes in zebrafish.
  • Analysis of zebrafish models for insights into MS pathology.

Main Results:

  • Zebrafish models provide significant insights into demyelination and remyelination.
  • These models offer new perspectives on the pathology of multiple sclerosis.
  • Research indicates potential for developing novel therapies for MS using zebrafish.

Conclusions:

  • Zebrafish are a significant model organism for studying MS.
  • Continued research in zebrafish models is vital for advancing MS understanding and treatment.
  • This research aims to improve the quality of life for individuals with MS.