Adrenal insufficiency due to invasion by lymphoma: documentation by CT scan

We have presented the first documented description of the induction of adrenal failure from invasion by a lymphoma. Although adrenal involvement may be common in this disease, which often involves the retroperitoneum, adrenal failure is still unusual. Our case suggests that clinical suspicion must be heightened when lymphoma is present. In particular, adrenal function tests are indicated for patients who have CT evidence of bilateral adrenal invasion from any source, including lymphoma.